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Cocaine is a powerfully addictive stimulant drug made from the leaves of the coca plant. It is illegal for recreational use in most countries and is known by street names such as “coke,” “flake,” “snow,” or “blow”.
Forms of cocaine
Cocaine hydrochloride: A fine, white, crystalline powder that can be snorted through the nose, rubbed on the gums, or dissolved in water and injected.
Crack cocaine: Processed from powdered cocaine to form small “rocks” or “pellets” that are heated and smoked. It is more addictive than powdered cocaine because it reaches the brain in seconds, causing a faster, more intense high.
Effects on the body and mind
Cocaine acts as a central nervous system stimulant, flooding the brain’s reward circuits with dopamine. The effects are typically short-lived and vary depending on how the drug is taken, how much is used, and the individual.
Short-term effects include:
Intense euphoria and increased energy.
Increased heart rate, blood pressure, and body temperature.
Constricted blood vessels and dilated pupils.
Restlessness, anxiety, and paranoia.
Decreased appetite.
Risk of a heart attack, stroke, seizures, and sudden death.
Long-term effects include:
Addiction, which can develop after only a short time.
Severe damage to the nose, including loss of smell and erosion of the nasal septum from snorting.
Lung damage and respiratory issues from smoking.
Infectious diseases like HIV and hepatitis C from injecting with shared needles.
Heart muscle inflammation, failure, and other cardiovascular issues.
Severe mental health issues, such as depression, anxiety, and psychosis.
Malnutrition and severe weight loss.
Addiction and withdrawal
Repeated cocaine use can lead to tolerance, meaning more of the drug is needed to achieve the same effect. Dependence can develop, resulting in withdrawal symptoms when use is stopped or significantly reduced.
Cocaine withdrawal symptoms typically include:
Intense cravings for the drug.
Fatigue and hypersomnia (excessive sleepiness).
Depressed mood, agitation, and anxiety.
Increased appetite.
Unpleasant dreams.
Cocaine addiction is a treatable medical condition. Treatment options often involve behavioral therapies and support groups to help individuals manage cravings and avoid triggers.
Overdose
A cocaine overdose can be fatal and can occur even with small amounts, especially for those with pre-existing health conditions. It is also highly dangerous to mix cocaine with alcohol, as this combination creates a more toxic substance called cocaethylene, which increases toxicity to the heart, liver, and other organs.
Overdose symptoms can include:
Irregular heart rhythm or pulse
Trouble breathing
Chest pain
Extreme agitation and paranoia
Seizures or tremors
Hallucinations
If you or someone you know is experiencing symptoms of a cocaine overdose, seek emergency medical help immediately by calling emergency services.

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